Re: Title: Orbitofrontal contributions to human working memory (2010)--> coordination of WM proc. vs. pure WM proc.

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On May 26, 2:35 am, likeprestige <plastic...@live.com.au> wrote:
> Title: Orbitofrontal contributions to human working memory
>
> Date: 2010
>
> Abstract:
>     Although cognitive neuroscience has made remarkable progress in
> understanding the involvement of the prefrontal cortex in human
> memory, the necessity of the orbitofrontal cortex for key competencies
> of working memory remains largely unexplored. We therefore studied
> human brain lesion patients to determine whether the orbitofrontal
> cortex is necessary for working memory function, administering
> subtests of the Wechsler memory scale, the Wechsler adult intelligence
> scale, and the n-back task to 3 participant groups: orbitofrontal
> lesions (n = 24), prefrontal lesions not involving orbitofrontal
> cortex (n = 40), and no brain lesions (n = 54). Orbitofrontal damage
> was reliably associated with deficits on neuropsychological tests
> involving the coordination of working memory maintenance,
> manipulation, and monitoring processes (n-back task) but not on pure
> tests of working memory maintenance (digit/spatial span forward) or
> manipulation (digit/spatial span backward and letter–number
> sequencing). Our findings elucidate a central component of the neural
> architecture of working memory, providing key neuropsychological
> evidence for the necessity of the orbitofrontal cortex in executive
> control functions underlying the joint maintenance, manipulation, and
> monitoring of information in working memory. (PsycINFO Database Record
> (c) 2011 APA, all rights reserved)
>
> Obtain full text from:http://www.decisionneurosciencelab.org/pdfs/Barbey_et_al_2010.pdf
>
> Google search title:http://www.google.com.au/search?q=Orbitofrontal+contributions+to+huma...
>
> If unsuccessful, let me know and I'll send it to you.

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