Re: Docosahexaenoic acid dietary supplementation enhances the effects of exercise on synaptic plasticity and cognition. (article)

indeed.

i do appreciate this.

thank you, again.

most interesting.

even tho i have not perceived any benefit from it...........

i might try some other formulations............

i have been taking fish oil for some time now...............many many
months.

On May 17, 2:48 pm, Pontus Granström <lepon...@gmail.com> wrote:
> Don't know, I'll have to investigate this, however it's nice that "our
> standing recommendation" running and fish oil seems to have solid scientific
> foundations.
>
> On Tue, May 17, 2011 at 9:43 PM, whoisbambam <smath...@gmail.com> wrote:
> > interesting.
>
> > thank you very much.
>
> > i wonder if dha is required, since epa can easily be converted to
> > dha...........
>
> > On May 17, 6:09 am, Pontus Granström <lepon...@gmail.com> wrote:
> > > Abstract
>
> > > Omega-3 fatty acids (i.e. docosahexaenoic acid; DHA), similar to
> > exercise,
> > > improve cognitive function, promote neuroplasticity, and protect against
> > > neurological lesion. In this study, we investigated a possible
> > synergistic
> > > action between DHA dietary supplementation and voluntary exercise on
> > > modulating synaptic plasticity and cognition. Rats received DHA dietary
> > > supplementation (1.25% DHA) with or without voluntary exercise for 12
> > days.
> > > We found that the DHA-enriched diet significantly increased spatial
> > learning
> > > ability, and these effects were enhanced by exercise. The DHA-enriched
> > diet
> > > increased levels of pro–brain-derived neurotrophic factor (BDNF) and
> > mature
> > > BDNF, whereas the additional application of exercise boosted the levels
> > of
> > > both. Furthermore, the levels of the activated forms of CREB and
> > > synapsin Iwere incremented by the
> > > DHA-enriched diet with greater elevation by the concurrent application of
> > > exercise. While the DHA diet reduced hippocampal oxidized protein levels,
> > a
> > > combination of a DHA diet and exercise resulted in a greater reduction
> > rate.
> > > The levels of activated forms of hippocampal Akt and CaMKII were
> > increased
> > > by the DHA-enriched diet, and with even greater elevation by a
> > combination
> > > of diet and exercise. Akt and CaMKII signaling are crucial step by which
> > > BDNF exerts its action on synaptic plasticity and learning and memory.
> > These
> > > results indicate that the DHA diet enhanced the effects of exercise on
> > > cognition and BDNF-related synaptic plasticity, a capacity that may be
> > used
> > > to promote mental health and reduce risk of neurological disorders.
>
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